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REWIND expanded the evidence base by studying dulaglutide (1.5 mg/week subcutaneous) in a broader population that included a substantial proportion of primary prevention patientsonly 31% of its 9,903 participants had established cardiovascular disease at baseline [3]
Who Might Consider It: People who don't tolerate the newer medications well, or those who want to start with a gentler option
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It is important to speak with an experienced doctor about the best ways to manage the possible semaglutide side effects, since certain management ways may help alleviate any negative symptoms experienced
Ridker PM, Macfadyen JG, Glynn RJ et al (2018) Inhibition of interleukin-1 by canakinumab and cardiovascular outcomes in patients with chronic kidney disease
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