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[163]) might be related to osmotic stress rather than pathological modification of the eye lens and that chronic aberration of osmotic pressure causes net loss of carnitine which can lead to triggering of cataracts

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Undeniably, Ca 2+ fluxes are crucial for almost all reported RCD pathways in erythrocytes, whereas in apoptosis, Ca 2+ elevation mediates primarily the mitochondrial outer membrane permeabilization (MOMP), triggering the intrinsic apoptosis [192]

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