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For payloads with alcohol functional groups, the aminomethoxy (AM) spacer offers an effective alternative
Introduction and history of the chemistry of nucleic acids therapeutics
Wilkes JM, Clark LE, Herrera JL
Pharmacokinetics and tolerability of the ADCs in SD rats
In this case, the aliquot of the samples were immediately mixed with 0.5 ml of 1% zinc acetate to capture the maximum amount of sulfide in the biological material and incubated at 37.5C for 10 min
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