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This activation stimulates insulin secretion in a glucose-dependent manner, suppresses glucagon release, slows gastric emptying, and most significantly for weight management, reduces appetite through effects on hypothalamic appetite centers
145 HuynhKKloseMKrogsgaardKDrejerJBybergSMadsbadSet al
The working theory is based on research showing that probiotics such as Akkermansia muciniphila and Clostridium butyricum influence the production of short-chain fatty acids, which in turn stimulate GLP-1 secretion
Mustacich D (2001)
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