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And even though this is a very small study, we see statistical significance and an improvement in HDL, which, as a cardiologist, I can tell you, is a very substantial HDL increase. The company also reported a reduction in the triglyceride-to-HDL ratio, a marker associated with insulin resistance

Outcomes were analyzed using cross-sectional and time-to-event methods

Trends & Treatment Insights for 2025 Real-world data show rapid adoption in type 2 diabetes care: between early 2022 and mid-2024, roughly 1 in 5 type 2 diabetes patients were on GLP-1 therapy

This approach helps minimize retatrutide side effects while allowing the body to adjust