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Wintrobe M M

130 The ultimate goal of biomedical research is clinical translation, and the clinical application of EVs in treating cardiac diseases is in its early stages

For each condition, nuclei were pooled from 5 female and 5 male mice, with two replicates per condition (LPC: baseline = saline injected, demyelination = 7 dpl, CPZ: baseline = normal chow, demyelination = 5 weeks of 0.2% CPZ)

A 2025 preclinical study reported modulation of senescence-related pathways consistent with improved cellular function, though translation to human aging remains uncertain [17]

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