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Increase in Mrp1 expression and 4-hydroxy-2-nonenal adduction in heart tissue of Adriamycin-treated C57BL/6 mice

75 LiC.TianY.LiangY.LiQ

This was done using the following equation: where Vv was the germinal epithelium's volume density and Sv was its surface density

10.1016/j.cell.2012.03.042 14

Both cells and islets were stimulated with 100 nM exendin-4 or vehicle for 10 minutes and subsequently labelled with MitoTracker Red CMXRos (Thermo Fisher Scientific), washed 1x with PBS and imaged in phenol red free RPMI-1640 in a Leica Stellaris 8 inverted confocal microscope with 63x/1.40 (islets) or 100x/1.40 (cells) oil immersion objectives