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Mechanistically, L-tryptophan upregulated the expression of GLP-1related genes (e.g., Gcg and Pcsk1 ) in intestinal L cells, further promoting GLP-1 production ( In contrast, some postbiotics may suppress GLP-1 signaling
, Relationship between perioperative semaglutide use and residual gastric content: A retrospective analysis of patients undergoing elective upper endoscopy, J
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In the central nervous system, GLP-1 RAs regulate response to food cues and decrease food intake
Research has spanned gastrointestinal, musculoskeletal, and neurological model systems
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