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Side Effects & Safety Mild GI discomfort most common, usually transient in the first week Slight stimulant effect increased energy/alertness, especially early on Headaches occasional, typically mild and dose-related Mild insomnia if taken too late in the day No human clinical safety data all safety information from preclinical studies and community reports No liver toxicity observed in animal studies at therapeutic doses Unknown drug interactions theoretically could interact with NAD+-dependent pathways Core Supplies for This Protocol The essentials for running any reconstituted injectable: cold storage, accurate syringes, alcohol prep pads, and metabolic tracking
The most widely available form of B12 is cyanocobalamin, but it is not very active or beneficial to the body
AUC 090min , area under the concentration/time curve at last observation
Hypoxia inhibits ferritinophagy, increases mitochondrial ferritin, and protects from ferroptosis
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