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The drugs, originally designed to treat diabetes and found to promote weight loss, have also shown benefits for heart risks, sleep apnea and alcohol and substance abuse

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Adherence to your treatment plan, taking the appropriate dose, and administering injections as prescribed will help you see the best results

Research into combining agonism of the GLP-1 receptor with GIP, glucagon and possibly other receptors is ongoing, as well as novel mechanisms of drug delivery, for example, by inhalation

Notably, treatment cohorts in RCTs typically report more pronounced effects than controls for the primary outcomes we assessed, and in our real-world study, there was a clear continuum of responsiveness to GLP-1s, suggesting a high degree of variation in terms of patient benefit from GLP-1s