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Arch Pharm Res 35(1):145154
GLP-1 (glucagon-like peptide-1) is a naturally occurring incretin hormone secreted by enteroendocrine L-cells in the small intestine in response to food intake, where it signals satiety to the brain through hypothalamic receptor binding, slows gastric emptying to prolong the feeling of fullness, and modulates the release of insulin and glucagon in a glucose-dependent manner that helps stabilize post-meal blood sugar without the hypoglycemia risk associated with older drug classes
2025 Jun 3;97(21):11099-11109
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Cystine/glutamate antiporter xCT (SLC7A11) facilitates oncogenic RAS transformation by preserving intracellular redox balance
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