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Many articles have now concluded that GLP-1 agonists are associated with early worsening of existing DR (EWDR)

Epidemiological studies have highlighted a complex relationship between GLP-1 RAs and cancer risk

Hence, considering the above observations, it can be inferred that curcumin given at a specific dose of 200 mg per kg may be beneficial in regulating cyclophosphamide-induced cystitis by its antidotal activity on inflammation, oxidative stress along with modulating the mechanical properties of bladder smooth muscle tissue (Arafa, 2009)

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