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2 A separate 2-week RCT testing three GlyNAC dose levels in 114 healthy older adults found good tolerability but no significant improvement in the primary endpoint (GSH:GSSG ratio) in the full study population, highlighting that responses may depend on baseline oxidative stress levels and study duration
This mechanistic separation means direct drug-drug interactions are unlikely from a pharmacokinetic perspective
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Int J Mol Sci 24(7):6551 Zhao C, Wu Y, Zhu S, Liu H, Xu S (2024) Irisin protects musculoskeletal homeostasis via a mitochondrial quality control mechanism
