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These drugs work by mimicking a naturally occurring hormone that regulates blood glucose levels and appetite

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Mounjaro is a once-weekly injection containing tirzepatide, which targets two hormones, GLP-1 and GIP , and it's shown the strongest average weight loss results in clinical trials, at around 22.5% over 72 weeks

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GLP-2 acts through GLP-2R, a highly specific GPCR located in the gastrointestinal tract, pancreas, and central nervous system (6063)