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We did not identify additional major safety concerns in the clinics intake, prescribing, or packaging workflow during testing

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We recommend touching base with your provider to discuss alternatives and/or strategies to prevent pregnancy while using this

The fact that the double-cysteine mutations only partially abolish the physiological function may imply that not all the expressed mutants have an intact disulfide bridge and that the observed conformation is only one possible inactive state on the cell surface, as supported by the EM data and MD simulations below