A study in Cell Metabolism demonstrated that GIP receptor activation in adipose tissue can promote fat oxidation under certain conditions (Samms et al., 2020) Synergy with GLP-1 When GIP and GLP-1 receptors are activated together, the combined effect on appetite suppression and insulin sensitivity exceeds what either achieves alone
However, it is not FDA-approved for any specific medical indication, and WADA prohibits it for competitive athletes
Heres the illustration for the Times article: Search ketogenic diet on the website clinicaltrials.gov and among the several hundred hits4, youll find trials assessing the safety and efficacy of virtually every imaginable chronic disease or disorder: A very much non-exhaustive list, in no particular order, includes autism and autism spectrum disorder, Alzheimers disease, major depressive disorder, multiple sclerosis, alcoholism, brain metastases, traumatic brain injury, rheumatoid arthritis, glioblastoma, anorexia nervosa, Parkinsons disease, heart failure, non-alcoholic fatty liver disease, metastatic pancreatic cancer, polycystic ovary syndrome, and, of course, obesity, insulin resistance, and diabetes
Diabetes is a key modifier of vaginal microbiome and infection susceptibility
Enhances skin brightness and reduces pigmentation