1 mg semaglutide equivalent tirzepatide Switching from to Tirzepatide: Is It a Good Idea? Efficacy of tirzepatide 5, 10

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& Reboucas, N

The SUSTAIN clinical trial program, which evaluated semaglutide in patients with type 2 diabetes, showed average systolic blood pressure reductions of 37 mmHg across multiple studies, with smaller decreases in diastolic blood pressure

These mechanisms are worth mentioning since if the results in this latest correspondence in the NEJM are indeed replicated, there is a large difference if these effects are occurring either a) Because pancreatic beta cells are dying less b) Because pancreatic beta cells are growing back c) Because pancreatic beta cells are not being targeted by the immune system anymore If replicated, I find a) and b) to be the most likely reasons

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