glp 1 drugs and menopause Postmenopausal women on the GLP-1 medication tirzepatide (Zepbound) for obesity lost more weight if they were also using hormone therapy, a retrospective cohort study indicated. https://www.medpagetoday.com/endocrinology/menopause/119594 glp 1 drugs menopause GLP-1s

The question of whether GLP-1 therapy qualifies as direct immunomodulation or whether the benefits are primarily mediated through weight loss and reduced adipose inflammation is still under active investigation

however, they did note a strong placebo effect

The latter includes five repurposed drugs (relugolix, goserelin, elagolix, triptorelin, leuprorelin depot) and two new chemical entities or combinations that have been developed specifically for uterine fibroids: relugolix combined tablet and linzagolix

AASLD Practice Guidance: palliative care and symptom-based management in decompensated cirrhosis

120 Upon activation, Nrf2 is shuttled into the nucleus, where it binds to the antioxidant response element and enhances the expression of antioxidant genes