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Data suggest that activation of GIP-R decreases inflammation in adipose tissue and cytokines levels (such as IL-6) and promotes the rise of serum adiponectin levels, a cytokine with anti-inflammatory effects and beneficial effects on diabetic nephropathy, which can explain potential beneficial effects on kidneys (even if GIP-R are not present) (47)

Research shows a bell-shaped dose-response curve with BPC-157, meaning excessive dosing may actually reduce or reverse therapeutic effects

PMID 39381848

Risk of major adverse cardiovascular events and all-cause mortality in patients with hidradenitis suppurativa

Biochemical studies on the cardioprotective effect of glutamine on tissue antioxidant defense system in isoprenaline-induced myocardial infarction in rats