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High-dose vitamin C therapy (50 to 200 mg/kg per day) has been instituted empirically, with conflicting data suggesting that it may raise intracellular glutathione levels (67)

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Subsequently, cDNA was synthesized using a poly-T Primer and the gene coding the latent jr PPO1-wt was amplified using specific primers (Table S4) and Q5 High-Fidelity DNA polymerase (NEB, Ipswich, USA)