muciniphila isolated from human feces significantly increases GLP-1 secretion from human enteroendocrine L cells (NCI-H716) in a dose-dependent manner and to a greater extent than the microbial products acetate and propionate (Yoon et al., 2021)
It is a synthetic version of the hormone exendin-4, which is found in the saliva of the Gila monster, a venomous lizard native to the southwestern United States
Subsequently, the study leveraged B-mode ultrasonography to accurately measure the patients cross-sectional area (CSA) of their vastus lateralis (a key thigh muscle)
On this occasion, the authors expand our understanding of glutathione biology and identify extracellular glutathione (GSH), abundant in the tumour microenvironment, as an alternative source of essential amino acids to sustain tumour cell proliferation
29 Besides human hydrolases, macrodomain-containing hydrolases from VEEV and SARS can remove the ADP-ribosylation of RNA catalyzed by PARPs, suggesting a potential mechanism of pathogenesis via inhibiting the antiviral activity of IFN-stimulated genes, PARPs