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These genes include 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1 ( HMGCLL1 ), thrombospondin 1 ( THBS1 ), uncoupling protein 3 ( UCP3 ), enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase ( EHHADH ), and sorting nexin 4 ( SNX4 )
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Nutritional supplementation of L-carnitine, the biologically active form of carnitine, is ameliorative for uremic patients, and can improve nerve conduction, neuropathic pain and immune function in diabetes patients while it is life-saving for patients suffering primary carnitine deficiency
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