aafp glp 1 weight loss GLP-1 Receptor Agonists for Obesity in Adolescents Balancing weight and muscle loss

References [1] An JH, Kim YJ, Kim KJ, et al

You need to be in a caloric deficit for fat loss but provide enough protein for muscle growth

Important markers may include waist circumference, appetite control, energy, digestion, blood pressure, glucose markers, cholesterol, strength, and body composition goals

The present review ultimately weighs early concerns against increasingly consistent evidence that GLP-1 RA use does not raise overall cancer risk, clarifies that breast cancer risk appears neutral, and further highlights key mechanisms, such as the reduction of hyperinsulinemia and immune-microenvironment modulation, through which these drugs may improve rather than exacerbate malignancy outcomes

Gastrointestinal Symptoms : Some individuals might experience nausea, vomiting, diarrhea, or an upset stomach