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By contrast, first-time prescribing of AOMs increased 21.7% over the same period, from 0.56% to 0.69%

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For example, the SELECT trial reported that semaglutide reduced the risk of MACE by 20% (Hazard Ratio (HR) 0.80, 95% confidence interval (CI) 0.720.90) in people with obesity but without diabetes, although several secondary outcomes did not reach statistical significance under hierarchical testing procedures

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Use the 6-8 week gradual reduction protocol outlined earlier

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Current research presents a complex picture that requires careful interpretation, as studies have yielded mixed results depending on the specific agent studied, patient population, duration of treatment, and methodology employed

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It develops when there is excess fat in liver cells due to too much fatty acid uptake in the liver, excess synthesis of fat in the liver, and not enough fat exported out of the liver

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