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Abstract Background The FLOW clinical trial recently demonstrated that the glucagon-like peptide-1 receptor agonist once-weekly semaglutide 1 mg was associated with kidney- and cardio-protective effects (the latter already shown in the SUSTAIN 6 trial) compared with placebo, both in addition to standard of care (SoC), in people with type 2 diabetes (T2D) and chronic kidney disease (CKD)
They are not intended to represent clinical evidence in humans, and Glow Blend has not been approved by the FDA, EMA, or any other regulatory authority for any indication
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Fibrocystin has been shown to associate with the polycystin complex (PC1-PC2) and its deficiency impact similar proliferative pathways to promote cyst formation, kidney enlargement, and progression to ESRD
Many clinicians actively recommend PPI therapy for semaglutide users with significant reflux symptoms
