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BDNF treatment has been shown to dose-dependently increase the mRNA and protein expression of Bcl-xL in the rat hippocampus through phosphorylation of NF-B at the Ser529 site and the activation of casein kinase II [241]

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our case highlights the need for further research to improve understanding of, develop data-driven treatment recommendations for, and improve long-term patient outcomes in this rare malignancy

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Three studies contained data for more than one brain region: the results for these different brain regions were included in the final meta-analysis, giving a total of 11 studies in the final list of brain regions with data available

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