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We next performed a structural similarity search across our in-house compound collection, as well as on commercial small-molecule libraries (1,000,000 compounds) and identified 141 additional hits, which were screened in the high-throughput activity assay at a single concentration of 10 M

Its longer half-life (~7 days) means slightly more stable blood levels between weekly injections

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This can help you identify patterns, track adherence to dietary goals, and make adjustments

MEK inhibitors markedly reduced tumor growth in high-MAP3K8 PDX models, compared with low-MAP3K8 PDX models