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A meta-analysis published in 2023 included individual participant-level data from three randomized controlled trials that evaluated the effect of at least two years of vitamin D supplementation on risk of new-onset diabetes among people with prediabetes (Pittas 2023)
doi: 10.1016/j.semcdb.2019.10.007 213 SalaVCrepaldiT
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Cost-effectiveness improves with: Age (older individuals see more dramatic relative improvement) Baseline deficiency (those with lower starting GH benefit more) Consistent training and nutrition (peptides amplify rather than replace fundamentals) Anti-aging and skin health Cost range: $150-500 monthly Duration: Ongoing or cyclical Cost-effectiveness: Subjective Value depends on how much you prioritize appearance and skin quality
