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Food & Drug Administration (FDA) approved the use of GLP-1 receptor agonist drugs, for treating type 2 diabetes

Despite being a pharmacologically varied class, antispasmodics are believed to alleviate the symptoms of IBS by lowering visceral hypersensitivity and smooth muscle contraction (68)

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First, although the experimental data are conflicting [90], it is possible that potentiation of SDF-1 by DPP-4 inhibitors may enhance the inflammatory and proliferative responses to kidney injury and may thereby aggravate the course of diabetic nephropathy [27, 28]